- Human pathology

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Wednesday 28 September 2005

- Mitochondrial sequences were retrieved from museum specimens of the enigmatic Andaman Islanders to analyze their evolutionary history. (12478481)

- D-loop and protein-coding data reveal that phenotypic similarities with African pygmoid groups are convergent. (12478481)

- Genetic and epigenetic data are interpreted as favoring the long-term isolation of the Andamanese, extensive population substructure, and/or two temporally distinct settlements. (12478481)

- An early colonization featured populations bearing mtDNA lineage M2, and this lineage is hypothesized to represent the phylogenetic signal of an early southern movement of humans through Asia. (12478481)


- Endicott P, Metspalu M, Stringer C, Macaulay V, Cooper A, Sanchez JJ. Multiplexed SNP Typing of Ancient DNA Clarifies the Origin of Andaman mtDNA Haplogroups amongst South Asian Tribal Populations. PLoS ONE. 2006 Dec 20;1:e81. PMID: 17218991

- Endicott P, Gilbert MT, Stringer C, Lalueza-Fox C, Willerslev E, Hansen AJ, Cooper A. The genetic origins of the Andaman Islanders. Am J Hum Genet. 2003 Jan;72(1):178-84. PMID: 12478481