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melanocytic nevi
Thursday 22 December 2005
melanocytic naevus; melanocytic naevi / nevus
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Types
congenital melanocytic nevus
melanocytic Spitz nevus
deep-penetrating melanocytic nevus
melanocytic combined nevus
pigmented spindle cell nevus
Halo nevus
dysplastic melanocytic nevus
melanocytic recurrent nevus
melanocytic blue nevus
Images
mitosis in melanocytic nevus
Molecular biology
acquired melanocytic nevus : BRAF mutations
congenital melanocytic nevus : NRAS mutations
Spitz nevus / Spitz tumor / Spitzoid tumors : tyrosine kinase fusion
LOH
6q22-23.3 (29%)
1p36 (27%)
10q23 (25%
11q23 (10%)
8p22-24 (7%)
See also
melanocytic tumors
- malignant melanocytic tumors (melanoma)
References
Loss of heterozygosity analysis of cutaneous melanoma and benign melanocytic nevi: laser capture microdissection demonstrates clonal genetic changes in acquired nevocellular nevi. Maitra A, Gazdar AF, Moore TO, Moore AY. Hum Pathol. 2002 Feb;33(2):191-7. PMID: 11957144
