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Crimean-Congo hemorrhagic fever virus

Monday 2 January 2006

Crimean-Congo hemorrhagic fever virus (CCHFV) is an important human pathogen, which is the cause of a tick-borne illness occurring in many areas of Africa, Asia, and Europe.

CCHF is characterized by a sudden onset of high fever, chills, and severe headache. Other symptoms can include gastrointestinal disorders, such as nausea, vomiting, and diarrhea.

In severe cases, hemorrhagic manifestations can occur and often present as large areas of ecchymosis, rather than frank bleeding.

Exposure to ticks, particularly those in the genus Hyalomma, or direct contact with virus-infected animals or people are considered the major risk factors.


- Flick R, Whitehouse CA. Crimean-Congo hemorrhagic fever virus. Curr Mol Med. 2005 Dec;5(8):753-60. PMID: 16375710