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endothelial signaling

Saturday 11 February 2006

Blood vessels perfuse all tissues in the body and mediate vital metabolic exchange between tissues and blood.

Increasing evidence, however, points to a direct role for paracrine signaling between blood vessel cells and surrounding target organ cells, during embryonic development and cell differentiation.


- Cleaver O, Melton DA. Endothelial signaling during development. Nat Med. 2003 Jun;9(6):661-8. PMID: 12778164