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diversion colitis

Friday 24 February 2006

Definition: Diversion colitis (DC) is a localized, relatively benign, iatrogenic condition which occurs in almost 100% of diverted colonic segments in patients who undergo ileostomy/colostomy for various reasons.

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- diversion colitis

Synopsis

- prominent colonic follicular lymphoid hyperplasia (100%)
- chronic mucosal inflammation (100%)
- acute mucosal inflammation (78%)
- Paneth cell metaplasia (26%)
- mild goblet cell depletion (22%)
- foci of colonic cryptitis (13%)
- colonic crypt abscesses (13%)
- mild colonic mucosal architectural distortion (22%)
- colonic mucosal aggregates of eosinophils (43%)

References

- Vujanic GM, Dojcinov SD. Diversion colitis in children: an iatrogenic appendix vermiformis? Histopathology. 2000 Jan;36(1):41-6. PMID: 10632750

- Komorowski RA. Histologic spectrum of diversion colitis. Am J Surg Pathol. 1990 Jun;14(6):548-54. PMID: 2337203