Humpath.com - Human pathology

Home > D. General pathology > Vascular pathology > TAAD

TAAD

Sunday 26 February 2006

Etiology

- germline mutations in MYH11 (myosin heavy chain 11)

  • association TAAS-patent ductus arteriosus

References

- Zhu L, Vranckx R, Van Kien PK, Lalande A, Boisset N, Mathieu F, Wegman M, Glancy L, Gasc JM, Brunotte F, Bruneval P, Wolf JE, Michel JB, Jeunemaitre X. Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus. Nat Genet. 2006 Jan 29; PMID: 16444274