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MIM.173335 6q22-q23

Wednesday 8 March 2006


- germline mutations in

- Variants of ENPP1 associated with:

  • childhood obesity
  • adult obesity
  • increase risk of glucose intolerance and type 2 diabetes


- Meyre D, Bouatia-Naji N, Tounian A, Samson C, Lecoeur C, Vatin V, Ghoussaini M, Wachter C, Hercberg S, Charpentier G, Patsch W, Pattou F, Charles MA, Tounian P, Clement K, Jouret B, Weill J, Maddux BA, Goldfine ID, Walley A, Boutin P, Dina C, Froguel P. Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes. Nat Genet. 2005 Aug;37(8):863-7. PMID: 16025115