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nodal vascular tumors

Friday 10 March 2006

Primary vascular tumors of lymph nodes

Types

- Kaposi sarcoma

- hemangiomas of capillary/cavernous, lobular capillary and cellular types

- angiomyomatous hamartoma

    • replacement of the nodal parenchyma by smooth muscle cells and fibrous tissue, in continuity with exuberant proliferation of muscular vessels in the hilum

- epithelioid vascular tumors

  • spindle and epithelioid hemangioendothelioma
    • additional component of spindle cells
  • polymorphous hemangioendothelioma
    • borderline malignant vascular tumor exhibiting solid, primitive vascular and angiomatous patterns and relatively bland cytologic features
  • lymphangiomas of lymph nodes
    • simultaneous multifocal and extra-nodal involvement
    • cystic endothelium-lined spaces filled predominantly with lymph fluid

Differential diagnosis

- benign vasoproliferative lesions
- angiosarcoma
- metastatic cancer

References

- Chan JK, Frizzera G, Fletcher CD, Rosai J. Primary vascular tumors of lymph nodes other than Kaposi’s sarcoma. Analysis of 39 cases and delineation of two new entities. Am J Surg Pathol. 1992 Apr;16(4):335-50. PMID: 1373579