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antibody conjugates

Sunday 12 March 2006

Immunotherapeutics represent the largest group of molecules currently in development as new drug entities.

These versatile molecules are being investigated for the treatment of a range of pathological conditions including cancer, infectious and inflammatory diseases.

Antibodies can be used to exert biological effects themselves or as delivery agents of conjugated drug molecules.

Site-specific delivery of therapeutic agents has been an ultimate goal of the pharmaceutical industry in order to maximize drug action and minimize side effects.

References

- McCarron PA, Olwill SA, Marouf WM, Buick RJ, Walker B, Scott CJ. Antibody conjugates and therapeutic strategies. Mol Interv. 2005 Dec;5(6):368-80. PMID: 16394252