Molecular processes

Articles

• promoter swapping
  18 August 2004

  Exemples
  promoter swapping between the genes for zinc finger protein PLAG1 and beta-catenin CTNNB1 in pleiomorphic adenoma with t(3;8)(p21;q12) translocation (#9020842#)
  PLAG1 at 8q12 and LIFR promoter at 5p13 PLAG1 gene overexpression under control of the LIFR promoter (#9525740#) in pleomorphic adenomas (#9525740#)
  PLAG1 in lipoblastomas
  USP6 in aneurysmal cyst of bones
  See also
  tumoral chromosomal (...)

• overexpression
  7 October 2005

  genic overexpression

• protein glycosylation
  27 January 2005

  proteic glyscosylation

• bacterial invasion
  30 November 2003

  References
  Cossart P, Pizarro-Cerda J, Lecuit M. Invasion of mammalian cells by Listeria monocytogenes : functional mimicry to subvert cellular functions. Trends Cell Biol. 2003 Jan ;13(1):23-31. PMID : #12480337#

• antibody class switching
  19 August 2004

  References
  Kaminski DA, Stavnezer J. Antibody class switching: uncoupling S region accessibility from transcription. Trends Genet. 2004 Aug;20(8):337-40. PMID: #15262403#

• transcription elongation
  2 July 2004

  References
  Belotserkovskaya R, Reinberg D. Facts about FACT and transcript elongation through chromatin. Curr Opin Genet Dev. 2004 Apr;14(2):139-46. PMID: #15196460#

• protein phosphorylation
  26 September 2005

  Protein phosphorylation affects most, if not all, cellular activities in eukaryotes and is essential for cell proliferation and development. An estimated 30% of cellular proteins are phosphorylated, representing the phosphoproteome, and phosphorylation can alter a protein’s function, activity, localization and stability.
  Specificity
  Phosphorylation events are key to most nuclear and cytoplasmic processes. Cellular protein kinases and phosphatases are involved in the regulation of (...)

• transcriptional derepression
  2 July 2004

  Pathology
  Familial Alzheimer disease
  Rett syndrome
  Klippel-Trenaunay syndrome
  facioscapulohumeral muscular dystrophy
  References
  Gabellini D, Green MR, Tupler R. When enough is enough: genetic diseases associated with transcriptional derepression. Curr Opin Genet Dev. 2004 Jun;14(3):301-7. PMID: #15172674#

• transcription-coupled NER
  26 March 2006

  TCNER, transcription-coupled nucleotide excision repair, transcription coupled repair (TCR)

• cotranslational protein processing
  1 February 2006

  References
  Drenth JP, Martina JA, van de Kerkhof R, Bonifacino JS, Jansen JB. Polycystic liver disease is a disorder of cotranslational protein processing. Trends Mol Med. 2005 Jan;11(1):37-42. PMID: #15649821#

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