Translocation-associated tumors

Articles

• aggressive angiomyxoma
  7 February 2006

  AAMs, ’aggressive’ angiomyxoma; deep aggressive angiomyxoma PO
  Definition: Aggressive angiomyxoma (AA) is a distinctive, locally aggressive, fibromyxoid tumor of the pelvic and genital soft tissues.
  Aggressive angiomyxoma is an infiltrative spindle cell neoplasm arising in the soft tissues of the lower genital tract, perineum and pelvis; approximately 30% recur locally but distant metastasis is exceptionally rare
  Digital case
  JRC:1443 : Aggresive angiomyxoma of pelvic soft tissues. (...)

• clear cell sarcoma of the kidney
  14 July 2004, by JA

  CCSK, renal clear cell sarcoma; bone-metastasizing renal tumour of childhood AGCOH PathConsult eMedicine
  Digital slides
  Case 66 (HPC:66) : Clear cell sarcoma of the kidney (CCSK)
  Definition: Clear cell sarcoma of the kidney (CCSK) is a malignant renal tumor of childhood with a propensity to metastasize to bone and other organs. CCSK is linked to internal tandem duplications (ITDs) of the BCOR gene.
  This tumor may also recur many years after its initial diagnosis. The average age (...)

• angiomatoid fibrous histiocytoma
  14 October 2003

  Definition: Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor of low malignant potential and uncertain differentiation.
  Images
  https://twitter.com/JMGardnerMD/status/735824693718974464
  https://twitter.com/LizMontgomeryMD/status/1123321496837996544
  https://twitter.com/histiocytosisX/status/883309952303079429
  https://twitter.com/histiocytosisX/status/865226837093384194
  https://twitter.com/histiocytosisX/status/753620834925805568 (...)

• mucoepidermoid carcinoma
  14 June 2006

  pulmonary mucoepidermoid carcinoma; mucoepidermoid carcinoma of the bronchi;
  Digital cases
  HPC:95: pulmonary mucoepidermoid carcinoma.
  JRC:6447 : pulmonary mucoepidermoid carcinoma.
  JRC:19401 : pulmonary mucoepidermoid carcinoma.
  Images
  Mucoepidermoid carcinoma
  https://twitter.com/chioseasi/status/715338200479301633
  https://twitter.com/Helena_Path/status/853996400216035330
  https://twitter.com/bunn_belinda/status/867813656968519680 (...)

• myxoid/round cell liposarcoma
  7 October 2005

  myxoid liposarcoma and round cell liposarcoma group; MRC-LPS
  Definition: Myxoid and round cell liposarcoma accounts for about 30% to 35% of all liposarcomas and, even if still classified by the World Health Organization (WHO) as 2 distinct subtypes, share both clinical and morphologic features.
  See also :
  myxoid liposarcoma
  round cell liposarcoma
  Lesions combining both patterns are frequent and wide agreement exists in considering round cell liposarcoma as the high grade counterpart (...)

• myxoid liposarcoma
  1 November 2007

  PO
  Definition: Myxoid liposarcoma displays variably aggressive behavior and responds poorly to available systemic therapies.
  Images
  myxoid liposarcoma https://twitter.com/histiocytosisX/status/748157284644196352 https://twitter.com/a_sleeping_dog/status/773402045911007232 https://twitter.com/JMGardnerMD/status/737075990086590466 https://twitter.com/DanglisFotiosMD/status/734976870110900225 https://twitter.com/solcosao/status/706608037868404736
  FISH FUS rearrangement (...)

• giant cell angiofibroma
  11 October 2005

  Definition: Giant cell angiofibroma is a phenotypic variant of solitary fibrous tumor (SFT).
  Giant cell angiofibroma seems most often to arise in the head and neck region (predominantly orbit) of adults and which, with the passage of time.
  It may well prove to be a variant of solitary fibrous tumour characterized by prominent multinucleate giant cells and lipofibromatosis.
  It is a rare tumour occurring predominantly in the hands or feet of infants and young children.
  it shows a high (...)

• NUTM1-associated midline carcinoma
  5 May 2009

  NUT-associated carcinoma NMC ; NUT midline carcinoma ; Nuclear protein in testis (NUT) midline carcinoma (NMC) ; NUT-associated sinonasal carcinoma
  Definition: NUT midline carcinoma (NMC) is a high-grade malignancy that is defined by rearrangement of the nuclear protein in testis (NUT) gene on chromosome 15q14.
  Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare and aggressive subset of poorly differentiated squamous cell carcinoma that is defined by t(15,19) and typically (...)

• ALK-associated pulmonary adenocarcinoma
  14 June 2011

  ALK-rearranged lung carcinomas, ALK-associated lung cancer
  A subset (1% to 5%) of non-small-cell lung carcinomas harbors the EML4-ALK fusion gene.
  All cases show at least a focal adenocarcinoma component, and rare cases had additional squamous and sarcomatoid differentiation, respectively.
  Solid or acinar growth pattern, cribriform structure, presence of mucous cells (signet-ring cells or goblet cells), abundant extracellular mucus, lack of lepidic growth, and lack of significant nuclear (...)

• cellular mesoblastic nephroma
  29 August 2007

  cellular congenital mesoblastic nephroma

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