MPNST, malignant schwannoma PO
Definition: Malignant tumor arising from peripheral nervous tissue or showing nerve sheath differenciation.
Digital cases
JRC:8437 : Malignant peripheral nerve sheath tumor.
JRC:8443 : Malignant peripheral nerve sheath tumor (sciatic nerve).
JRC:8447 : Malignant peripheral nerve sheath tumor.
JRC:8450 : Malignant peripheral nerve sheath tumor.
JRC:8824 : Malignant peripheral nerve sheath tumor (oral cavity).
JRC:7954 : Malignant peripheral (...)
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malignant peripheral nerve sheath tumor
15 December 2003 -
hepatoblastoma
16 March 2004hepatoblastomas
Definition: Hepatoblastoma is a malignant embryonal liver tumor that occurs almost exclusively in infants and very young children.
Image
Macroscopy : https://twitter.com/DraEosina/status/762631086207893506
Cytology: https://twitter.com/AdamGomezMD/status/720632495671087104
https://twitter.com/MArnold_PedPath/status/736000944303808512
Hepatoblastoma is composed of epithelial and mesenchymal elements in varying proportions and at various stages of differentiation. The (...) -
pigmented spindle cell nevus
1 July 2004pigmented spindle cell nevus of Reed
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hydatiform mole
28 April 2004molar gestation; hydatiform moles WKP
Images
partial hydatiform mole by Ed Euthman
complete hydatiform mole https://twitter.com/luishcruzc/status/738155933801418752 https://twitter.com/KUSAURAP/status/778827207976230916
Definition: Hydatiform mole is a gestational trophoblastic disorder.
Accurate diagnosis and classification of hydatidiform mole (HM) are important because the risk of persistent gestational trophoblastic disease, including choriocarcinoma, is significantly (...) -
clear cell sarcoma of the kidney
14 July 2004, by JACCSK, renal clear cell sarcoma; bone-metastasizing renal tumour of childhood AGCOH PathConsult eMedicine
Digital slides
Case 66 (HPC:66) : Clear cell sarcoma of the kidney (CCSK)
Definition: Clear cell sarcoma of the kidney (CCSK) is a malignant renal tumor of childhood with a propensity to metastasize to bone and other organs. CCSK is linked to internal tandem duplications (ITDs) of the BCOR gene.
This tumor may also recur many years after its initial diagnosis. The average age (...) -
papillary thyroid carcinoma
15 March 2004TPC; PTC; thyroid papillary carcinoma
Types
classic PTC / classic papillary thyroid carcinoma
FV-PTC / follicular variant of papillary thyroid carcinoma
IFV-PTC / infiltrative FV-PTC
EFV-PTV / encapsulated FV-PTC
IEFV-PTC / invasive encapsulated FV-PTC
NIEFV-PTC / non-invasive encapsulated FV-PTC
Images
typical papillary thyroid carcinoma
https://twitter.com/nisspath/status/695415489837674496
FNA of papillary thyroid carcinoma (...) -
Spitz nevus
16 June 2004Spindle and epithelioid cell nevus, spitz tumor, spitz’s nevus, spindle cell nevus, juvenile melanoma, benign juvenile melanoma, epitheliod junctional nevus; Spitz tumor WKP PO
Definition: Spitz nevus is usually a pink papule on the extremities or face of young patients. It has little pigmentation, spindle and epithelioid cells, is usually compound, and may have eosinophilic globules known as Kamino bodies.
Images
Spitz nevus: Melanocytes with ample cytoplasm. Note the collagenous (...) -
fundic gland polyp
8 September 2004cystic glandular fundic polyposis; Fundic gland polyposis, cysts of gastric glands, gastric cystic polyposis, cystic body gland polyp, cystic body gland polyposis; fundic glandulocystic polyp; fundic gland polyp PO
Definition: Fundic glandulocystic polyps (or Fundic gland polyps - FGPs) are tiny multiple sessile polyps of the acid-secreting gastric mucosa. FGPs are sessile polyps arising in the oxyntic mucosa that can be single or multiple.
Images
Fundic gland polyp; in (...) -
gastric adenocarcinoma
22 April 2004gastric cancer, gastric carcinomas PO
Images
M 14y/o gastric adenocarcinoma with bone metastasis https://twitter.com/Sandro_CZ/status/778725943980417024
Digital cases
JRC:10442 : cutaneous metastasis of a gastric adenocarcinoma.
Etiology
Gastric cancer is thought to result from a combination of environmental factors and the accumulation of specific genetic alterations due to increasing genetic instability, and consequently affects mainly older patients.
Microscopical subtypes (...) -
nodular fasciitis
13 July 2004subcutaneous pseudosarcomatous fibromatosis, proliferative fasciitis. Ent. 1955 WKP PO
Definition: Nodular fasciitis is a benign proliferation of fibroblasts in the subcutaneous tissues, commonly associated with the deep fascia. Nodular fasciitis is a benign mesenchymal tumor.
Nodular fasciitis (NF) is a relatively common mass-forming and self-limited subcutaneous pseudosarcomatous myofibroblastic proliferation of unknown pathogenesis. Due to its rapid growth and high mitotic (...)