Cellular functions

Articles

• phagocytosis
  23 April 2004

  WKP
  Definition: Phagocytosis is a specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria. It is therefore distinct from other forms of endocytosis such as pinocytosis, the vesicular internalization of various liquids, and recptor-dependent endocytosis.
  Phagocytosis involves three distinct but interrelated steps:
  (1) recognition and attachment of the particle to be ingested by the leukocyte;
  (2) its engulfment, with subsequent (...)

• immune cell interactions
  28 December 2004

  immune-cell interactions

• neural crest cell migration
  10 July 2003

  Pathology
  anomalies of neural crest migration
  See also
  cell migration

• cellular aging
  7 March 2004

  Cellular aging is the result of a progressive decline in the proliferative capacity and life span of cells and the effects of continuous exposure to exogenous influences that result in the progressive accumulation of cellular and molecular damage. Structural and Biochemical Changes with Cellular Aging
  A number of cell functions decline progressively with age.
  Oxidative phosphorylation by mitochondria is reduced, as is synthesis of nucleic acids and structural and enzymatic proteins, (...)

• cell cycle
  13 July 2003

  cellular cycle

• neutrophil phagocytosis
  14 March 2007

  Phagocytosis of microbes by professional phagocytes such as neutrophils is crucial for the survival of the host.
  Microscopically, pseudopod extension, particulate engulfment and phagosome closure all require seemingly large expansions of the cell surface area.
  See also
  membrane stretching
  lipid bilayers
  exocytosis
  phagosomal fusion with endoplasmic reticulum membrane
  phagocytosis
  neutrophils
  References
  Hallett MB, Dewitt S. Ironing out the wrinkles of neutrophil (...)

• leukocyte migration
  25 January 2006

  The Src-family kinases (SFKs) Fgr and Hck inhibit chemokine signaling in polymorphonuclear leukocytes and dendritic cells by phosphorylation of PIR-B, an inhibitory receptor expressed on leukocytes.
  In resting cells, PIR-B phosphorylation is constitutive but is decreased transiently by addition of chemokines. In Fgr/Hck-deficient cells, constitutive PIR-B phosphorylation is markedly decreased.
  See also
  chemokine signaling
  cell migration
  cell invasion
  References
  Brown EJ. (...)

• leucocytic adhesion
  30 January 2005

  leucocyte adhesion, leukocyte adhesion

• lymphocyte migration
  1 December 2003

  References
  Reif K, Cyster J. The CDM protein DOCK2 in lymphocyte migration. Trends Cell Biol. 2002 Aug;12(8):368-73. PMID: #12191913#

• lymphocyte activation
  2 December 2003

  References
  Krawczyk C, Penninger JM. Molecular controls of antigen receptor clustering and autoimmunity. Trends Cell Biol. 2001 May;11(5):212-20. PMID: #11316610#

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