Functional proteic groups

Articles

• RNA-binding proteins
  30 November 2003

  Function
  RNA-binding proteins are involved in various aspects of RNA metabolism such as processing, translational control, stabilization, localization and transport.
  Many of these proteins bind several RNA targets and have multiple functions.
  Feautures
  RNA transport
  RNA localization
  RNA metabolism
  RNA splicing
  References
  Lunde BM, Moore C, Varani G. RNA-binding proteins: modular design for efficient function. Nat Rev Mol Cell Biol. 2007 May 2; PMID: #17473849#
  Musunuru K. (...)

• vascular homing peptides
  7 March 2007

  References
  Ruoslahti E, Duza T, Zhang L. Vascular homing peptides with cell-penetrating properties. Curr Pharm Des. 2005;11(28):3655-60.
  PMID: #16305501#
  Ruoslahti E. Vascular zip codes in angiogenesis and metastasis. Biochem Soc Trans. 2004 Jun;32(Pt3):397-402. PMID: #15157146#
  Ruoslahti E. Specialization of tumour vasculature. Nat Rev Cancer. 2002 Feb;2(2):83-90. PMID: #12635171#
  Ruoslahti E. Drug targeting to specific vascular sites. Drug Discov Today. 2002 Nov (...)

• myogenic regulatory factors
  7 March 2007

  MTFs

• odorant receptors
  23 November 2003

  References
  Kratz E, Dugas JC, Ngai J. Odorant receptor gene regulation: implications from genomic organization. Trends Genet. 2002 Jan;18(1):29-34. PMID: #11750698#

• nuclear hormone receptors
  23 November 2003

  NHRs

• HDACs
  23 November 2003

  histone deacetylases

• chaperonins
  23 November 2003

  Chaperonins are multisubunit, cylinder-shaped molecular chaperones involved in folding newly synthesized polypeptides.
  Chaperonins are key components of the cellular chaperone machinery. These large, cylindrical complexes contain a central cavity that binds to unfolded polypeptides and sequesters them from the cellular environment. Substrate folding then occurs in this central cavity in an ATP-dependent manner.
  The eukaryotic chaperonin TCP-1 ring complex (TRiC, also called CCT) is (...)

• TOPs
  26 March 2006

  topoisomerases

• adaptator proteins
  16 July 2004

  adaptators

• muscarinic receptors
  6 September 2005

  References
  Dean B, Bymaster FP, Scarr E. Muscarinic receptors in schizophrenia. Curr Mol Med. 2003 Aug;3(5):419-26. PMID: #12942995#

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