Functional proteic groups

Articles

• TOPs
  26 March 2006

  topoisomerases

• ribosomal initiating factors
  29 August 2005

  Exemples
  EIF2A (eukaryotic translation initiation factor IA)

• protein phosphatases
  1 December 2003

  Mitosis exit
  The mitosis-to-interphase transition involves dramatic cellular reorganization from a state that supports chromosome segregation to a state that complies with all functions of an interphase cell.
  This process, termed mitotic exit, depends on the removal of mitotic phosphorylations from a broad range of substrates.
  Mitotic exit regulation involves inactivation of mitotic kinases and activation of counteracting protein phosphatases.
  The key mitotic exit phosphatase in budding (...)

• potassium channels
  2 December 2003

  K+ channels

• RNA-binding proteins
  30 November 2003

  Function
  RNA-binding proteins are involved in various aspects of RNA metabolism such as processing, translational control, stabilization, localization and transport.
  Many of these proteins bind several RNA targets and have multiple functions.
  Feautures
  RNA transport
  RNA localization
  RNA metabolism
  RNA splicing
  References
  Lunde BM, Moore C, Varani G. RNA-binding proteins: modular design for efficient function. Nat Rev Mol Cell Biol. 2007 May 2; PMID: #17473849#
  Musunuru K. (...)

• intramembrane-cleaving proteases
  29 November 2003

  References
  Martoglio B, Golde TE. Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R201-6. PMID: #12966028#
  Weihofen A, Martoglio B. Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides. Trends Cell Biol. 2003 Feb;13(2):71-8. PMID: (...)

• ADP-ribosyl cyclases
  30 August 2005

  References
  Schuber F, Lund FE. Structure and enzymology of ADP-ribosyl cyclases: conserved enzymes that produce multiple calcium mobilizing metabolites. Curr Mol Med. 2004 May;4(3):249-61. PMID: #15101683#
  Potter BV, Walseth TF. Medicinal chemistry and pharmacology of cyclic ADP-ribose. Curr Mol Med. 2004 May;4(3):303-11. PMID: #15101687#

• calcium channels
  30 August 2005

  calcium pumps

• calcium regulating proteins
  6 September 2005

  Ca++ regulating proteins

• muscarinic receptors
  6 September 2005

  References
  Dean B, Bymaster FP, Scarr E. Muscarinic receptors in schizophrenia. Curr Mol Med. 2003 Aug;3(5):419-26. PMID: #12942995#

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