Functional proteic groups

Articles

• ADP-ribosyl cyclases
  30 August 2005

  References
  Schuber F, Lund FE. Structure and enzymology of ADP-ribosyl cyclases: conserved enzymes that produce multiple calcium mobilizing metabolites. Curr Mol Med. 2004 May;4(3):249-61. PMID: #15101683#
  Potter BV, Walseth TF. Medicinal chemistry and pharmacology of cyclic ADP-ribose. Curr Mol Med. 2004 May;4(3):303-11. PMID: #15101687#

• calcium channels
  30 August 2005

  calcium pumps

• ribosomal initiating factors
  29 August 2005

  Exemples
  EIF2A (eukaryotic translation initiation factor IA)

• TOPs
  26 March 2006

  topoisomerases

• muscarinic receptors
  6 September 2005

  References
  Dean B, Bymaster FP, Scarr E. Muscarinic receptors in schizophrenia. Curr Mol Med. 2003 Aug;3(5):419-26. PMID: #12942995#

• calcium regulating proteins
  6 September 2005

  Ca++ regulating proteins

• morphogens
  29 October 2003

  morphogen gradients

• vesicular coat proteins
  29 October 2003

  Proteins and lipids to be transported are sorted to specific sites on the donor membrane, or compartment, and transport vesicles bud with the aid of cytosolic complexes of coat proteins.
  Vesicles move along cytoskeletal tracks, either microtubules or actin filaments, with the help of motor proteins.
  The vesicle is tethered and docked near the target membrane and subsequently fuses with the acceptor bilayer, releasing its contents into the target, or acceptor, compartment.
  Vesicular coat (...)

• oncogenes
  29 October 2003

  Pathology
  activation mutation
  overexpression
  fusion gene in which the promoter region of genes coding for the subunits of immunoglobulins (IGHG1, IGLC1, IGKC) or TCR (TCRA, TCRB, TCRC, TCRD) are juxtaposed to the entire coding sequence of a second gene that is subsequently overexpressed in lymphoid cells causing lymphomas or lymphoid leukemias
  fusion gene in which the promoter region of a first gene is juxtaposed to the entire coding sequence of a second gene that is subsequently (...)

• Na+ channels
  22 March 2005

  References
  Herfst LJ, Rook MB, Jongsma HJ. Trafficking and functional expression of cardiac Na+ channels. J Mol Cell Cardiol. 2004 Feb;36(2):185-93. PMID: #14871545#

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