Functional proteic groups

Articles

• oncogenes
  29 October 2003

  Pathology
  activation mutation
  overexpression
  fusion gene in which the promoter region of genes coding for the subunits of immunoglobulins (IGHG1, IGLC1, IGKC) or TCR (TCRA, TCRB, TCRC, TCRD) are juxtaposed to the entire coding sequence of a second gene that is subsequently overexpressed in lymphoid cells causing lymphomas or lymphoid leukemias
  fusion gene in which the promoter region of a first gene is juxtaposed to the entire coding sequence of a second gene that is subsequently (...)

• cytolinkers
  18 March 2004

  Members
  plakins

• chemokines
  18 November 2003

  Chemotactic cytokines

• vesicular coat proteins
  29 October 2003

  Proteins and lipids to be transported are sorted to specific sites on the donor membrane, or compartment, and transport vesicles bud with the aid of cytosolic complexes of coat proteins.
  Vesicles move along cytoskeletal tracks, either microtubules or actin filaments, with the help of motor proteins.
  The vesicle is tethered and docked near the target membrane and subsequently fuses with the acceptor bilayer, releasing its contents into the target, or acceptor, compartment.
  Vesicular coat (...)

• melanosome-associated proteins
  13 November 2003

  Members
  HMB45
  melan-A
  See also
  melanosomes
  References
  Raposo G, Marks MS. Melanosomes—dark organelles enlighten endosomal membrane transport. Nat Rev Mol Cell Biol. 2007 Oct;8(10):786-97. PMID: #17878918#

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